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Endoscopes :

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ESI-ION TRAP MS - ESQUIRE6000

ESI-ION TRAP MS - ESQUIRE6000

Esquire6000 The high Performance ESI-Ion Trap MSn System Today, researchers have clear demands for LC/MSn: Sensitivity and fast scan rates to extract more information from each HPLC peak. Smart software tools to simplify data interpretation and management. Streamlined workflow in times of ever- growing sample numbers and throughput. See how the esquire6000™ answers these needs with outstanding scan power, sensitivity, and usability. Industry-leading scan power Explore the high performance of our 3rd generation benchtop ion trap. Perform rapid sample screening, as well as detailed structural and quantitative investigations. Applications-driven software suite Utilize powerful software tools for quick and intuitive method setup, data interpretation and reporting of results. An analytical platform tailored to your needs Benefit from the esquire‘s smooth integration with a broad variety of LC systems, sample preparation modules, and API sources. Chromatography Choices The most widely used LC systems, autosamplers and fraction collectors are now fully integrated with the esquire6000: The Compass software enables complete and intuitive LC/MS method setup and system control. The esquire6000 can be coupled to the Capillary Electrophoresis systems and is part of the world‘s first fully-integrated LC-NMR/MS system introduced by Bruker Biospin and Bruker Daltonics. Ion Sources The esquire6000 uses the Agilent electrospray (ESI) ion source, which provides outstanding robustness, sensitivity and reproducibility over a wide range of LC operating conditions. The orthogonal sprayer design speeds up method development while minimizing chemical noise, regardless of the separation conditions. The rugged design with fixed sprayer position prevents contamination and thus extends the maintenance cycle time. Enhanced sensivitity for all applications down to the very low pg limit is possible. Tuning has become easier and largely uncritical across a wide m/z range. Switching between all sources is fast and easy, due to the hinged swingout spray chamber design. A whole varitey of API sources covers the widest range of LC/MS applications, including various low-flow options. The Ion Trap Superior combination of mass range, scan speed and resolution. The ion trap continues to offer the unrivaled standard mass range up to m/z 3000. Monoisotopic resolution throughout this standard mass range gives you the full picture at once. The extended mass range reaches up to m/z 6000. Fast scanning Ultrafast scan cycles for both MS and MS/MS account for an extremely high duty cycle. More than 100 mass scans can be captured across a typical LC peak. This fast scanning also improves the dynamic range and reduces measurement variance. MSn performance Fragmentation is supported up to the MS11 stage, allowing for detailed investigation of target compounds. Monoisotopic isolation is ensured throughout the standard mass range. Sensitivity The highly efficient ion transfer and trapping, as well as short scan times contribute to the truly superior sensitivity in the low pg range. Multiple stages of structural information Multiple fragmentation experiments up to MS11 help to gather structural information on ingredients of natural products, drugs, food and other samples. Because of the single-step dissociation in an ion trap, fragmentation pathways can be elucidated easily by MSn. An optional Wide-band Fragmentation™ across a m/z range of up to 300 u ensures the simultaneous fragmentation of the precursor and ions which are derived from the pure loss of water or amine groups if those occur dominantly. Fully automated ion-tree experiments and data-dependent scans help gaining structural information very quickly. In order to extract only the most relevant information, intelligent AutoMS/MS options can be used for MS/MS precursor ion selection and fragmentation. >>>
View the product on bdal.com Bruker Daltonics Inc Groupe - Bruker Optics
AUTOSCOPE 2 ENDOSCOPE REPROCESSERS

AUTOSCOPE 2 ENDOSCOPE REPROCESSERS

A versatile solution for the reprocessing of flexible endoscopes, videoscopes and other rigid 'scopes and instruments. Autoscope 2 is a range of fully automated systems designed to satisfy the highest standards of Infection Control and Health & Safety regulations. High level disinfection/sterilisation Integral printer for audit control Advanced control system/display panel Integral fume containment system Compatible with all disinfectant Bacteria-free water filtration Self-disinfection function Alcohol Flush, Leak Test and Raiser Bridge Options Two (F2) and four (F4) 'scope models available Suitable configurations for invasive and semi-invasive procedures Quality Assurance and Service back up Fume Containment To ensure your safety, Autoscopes are equipped with integral disinfectant fume removal and monitoring systems. A specialist airflow and Activated Carbon filter system ensures total COSHH compliance for all types of disinfectant fumes. Independent testing shows Autoscopes are fully able to comply with changes in EH40 to 0.05 ppm MEL for glutaraldehyde. Disinfectant Compatibility Autoscope 2 systems are fully compatible with all recognised disinfectants/sterilants including peracetic acid, peroxygen compounds, chlorine dioxide and 2% activated glutaraldehyde. This versatility enables the operator to opt for high level disinfection for standard endoscopy procedures or a sterile process for invasive or semi-invasive procedures. Broad compatibility with disinfectants / sterilants ensures you are not committed to a single source of disinfectant supply. >>>
View the product on labcaire.co.uk Labcaire Systems Ltd
SPECIALIZED FLEXIBLE ENDOSCOPE - SRS SYSTEM

SPECIALIZED FLEXIBLE ENDOSCOPE - SRS SYSTEM

The SRS system is a specialized flexible endoscope designed to perform an endoluminal partial anterior fundoplication for the treatment of GERD. The system resembles a standard gastroscope and includes a video processor, light source and suction-irrigation apparatus. The specialized parts of the system include a stapler and ultrasound sight for alignment. When the procedure is performed, a disposable cartridge of staples is inserted into the rigid section of the scope (measuring about 6cm). The average time of a complete procedure is 35 minutes. Distal Tip The distal tip includes all the elements of a standard gastroscope and in addition includes the ultrasound measurement device, the anvil of the stapler and specialized screws for anchoring the scope while the procedure is performed. All this is included in a distal tip measuring only 15mm in diameter. Procedure The SRS is a method and apparatus for performing partial anterior fundoplication that duplicates one of the existing standard procedures for treatment of GERD, but at the same time does not require anesthesia or violation of the abdominal cavity. 1. The SRS endoscope is introduced into the stomach much like a standard gastroscope. 2. The operator selects a stapling site in the esophagus, 2.3 - 3.0 cm above the GE junction. 3. The operator inputs the distance from the incisors. 4. The endoscope is advanced into the stomach, and retroflexed to 180°. 5. It is then pulled back so that the cartridge is at the selected stapling site. 6. The endoscope is further flexed to 270°, until the tip is aligned with the cartridge. 7. The ultrasonic sight verifies that alignment is perfect and that the distance between the anvil and the tip is small enough. 8. The operator then cranks a flywheel which extrudes two tiny screws, which penetrate the tissue, and lock the anvil and cartridge together. 9. The staples are then fired, the screws are withdrawn, and the scope is extended, and withdrawn. 10. The SRS is reloaded with a new cartridge, and the procedure is repeated. 11. The final result is an antero-lateral wrap, which tapers from 120 to 180 degrees, and augments the angle of His. >>>
View the product on medigus.com Medigus
OPTICAL COHERENCE TOMOGRAPHY - TOPCON 3D OCT-1000

OPTICAL COHERENCE TOMOGRAPHY - TOPCON 3D OCT-1000

Optical Coherence Tomography Topcon 3D OCT-1000 Recent advances in intravitrial therapy have given ophthalmologists real weapons to effectively treat many ocular diseases. These advances have heightened the need to accurately monitor your patient's response to therapy, identity lesions as early as possible as well as monitor subtle changes to the various layers of the retina. In order to see everything you need a system, instrument and software, which give you the power to see a wide area of the retina as well as the vitreous. You also need a system that gives you the power to scan the exact same area of the retina every time so that you can monitor your patient's progress over the course of their treatment. TOPCON, the world leader in spectral domain OCT, is proud to introduce the 3D OCT-1000 cutting-edge technology to improve the quality of vision and quality of life. • Ultra high-speed scan rate • Superior axial and lateral resolution • Fast cross-sectional (2D) scan • True colour 45°non-mydriatic retinal photo for pin point registration of the scan • Connection to IMAGEnet >>>
View the product on topcon.co.uk TOPCON (GB) LTD
ESI-ION TRAP MS - HCT

ESI-ION TRAP MS - HCT

The next Generation High Capacity Trap Aiming for high productivity and success in LC-MS, your requirements are: Maximum LC-MSn information from your samples. Ultrasensitive measurements. Smooth data handling and mining. Intelligent data interpretation and visualization Unique Performances The HCT LC-MSn system perfectly answers these needs. Our next-generation high capacity ion trap (HCT) mass spectrometer offers dramatically improved performance for proteomics, metabolite profi ling and other demanding LC-MSn applications: Speed: Ultra-fast acquisition of MS and MS/MS data across the fastest of HPLC peaks in real-time LC-MSn Sensitivity: Low attomole/femtogram sensitivity Spectral information: Superb quality of single mass spectra in combination with unique scan modes Dynamic range: High in-scan dynamic range for identification of low abundance compounds in biological samples. All embedded in a software environment tailored for proteomics and metabolite profiling. Ultimate Speed New, fast scan rates enable real-time LC-MSn across the fastest of HPLC peaks. The breakthrough UltraScan™ mode provides full scan MS and MS/MS spectra at a speed of 26,000 amu/sec with better than unit resolution. The Fast Enhanced Mode allows reliable charge state recognition of charges up to 3+, with a mass accuracy better than any quadrupole ion trap. PeptideScan™ combines these two scan modes for fast peptide separations. Full scan MS are acquired in the Fast Enhanced scan, while AutoMS/MS scans are performed using the faster UltraScan. This ultra-fast data acquisition delivers more productivity for your application: High-quality data even from trace components, as more MS/MS spectra are averaged across an LC peak. On-line, real-time LC-MSn from complex samples, as there is enough time for full scan MS and data-dependent MS/MS spectra acquisition within a single LC-MS run. Supreme Sensitivity Substantially improved ion storage capacity provides highest sensitivity for protein and metabolite research. The new trap geometry of the HCT enables a 10-fold higher ion storage capacity over older trap designs – providing the highest sensitivity of all ion traps in both full scan MS and MS/MS. This sensitivity directly translates into More certainty in protein identification and characterization through enhanced sequence coverage. Discovery of low abundance peptides and proteins, like phosphopeptides. More confidence in identification of trace metabolites. Better quantitation results. >>>
View the product on bdal.com Bruker Daltonics Inc Groupe - Bruker Optics
AUTOSCOPE JETAER AUTOMATED ENDOSCOPE REPROCESSOR

AUTOSCOPE JETAER AUTOMATED ENDOSCOPE REPROCESSOR

Single chamber Automated Endoscope Reprocessor incorporating single shot generator and water filtration unit for the reprocessing of up to 2 flexible endoscopes Autoscope JetAER builds on the assets of previous generations of Autoscope models integrating the latest available technology and complying with the strict washing procedures set out within HTM2030 and EN 15883 (parts 1 & 4). Autoscope JetAER incorporates a two basket design with automatic docking of channel irrigation connections and is capable of processing up to two endoscopes independently. All operating cycles are carried out within an enclosed stainless steel chamber with a fully automated door, preventing unauthorised or accidental access and the safe containment of any fumes given off by the disinfectants being used. Each basket is suitable for scope storage and transportation without the need to handle the scope. Despite a small footprint, each unit has a fully integrated single-use disinfectant generation system including validation, for use with a range of Labcaire approved disinfectants. In addition, there is a fully automated self-disinfect process therefore removing the need for separate chemical mixing and storage. Each model has an integrated, user-friendly Windows XP operating system with full colour control screen at eye level. A cycle validation printer complete with electronic data storage ensures all variables are reported from a successful or failed operating cycle. Automatic identification of endoscopes and operators is performed by means of a tag reader wand. This helps to reduce the endoscope processing time, as there is no need to key in various codes. Features • Powerful jet wash system with high pressure showerhead to wash and disinfect scopes, connectors, basket and chamber. • Integrated bacteria free water filtration system within main cabinet • Fully integrated single-use disinfectant generation system • Small footprint 940 x 700mm • Tag Reader • Fully automated self-disinfect process • User friendly Windows XP operating system • Advanced irrigation monitoring system tailored to individual endoscopes • Glass viewing window allowing visual checks during wash cycle • Fully automated fume containment and monitoring system with fan speed control for power saving and quiet operation • Energy save standby function • Removable access panels giving easy access to all areas for servicing • Integral high intensity lighting • All dosing, liquid levels / temperatures fully monitored during auto cycles • Key holder machine management system for hospital protocol, set-up and servicing • Flexible control system hardware and software providing easy system expansion or update >>>
View the product on labcaire.co.uk Labcaire Systems Ltd
ESI-ION TRAP MS - HCTULTRA

ESI-ION TRAP MS - HCTULTRA

HCTultra The ultra Performance High Capacity Trap Exceed the limits of all previous ion trap technology – set a new standard for high-information content LC-MSn! For today’s challenges in proteomics and metabolomics work, the HCTultra is best prepared to partner the researcher in the fields of: protein identification protein characterization de novo peptide sequencing differential proteomics metabolite profiling The new cutting-edge HCTultra™ adds the best ever speed and sensitivity available anywhere to the trusted portfolio of LC-ESI-MSn ion traps from Bruker Daltonics. Sensitivity & Speed The brand new HCTultra is the most sensitive ion trap on the market for MS and MS/MS scans. Full scan MS sensitivity is a must for all data dependant experiments, it enables intelligent acquisition of MS/MS data especially on low abundant precursor ions. Together with the dramatic increase in MS/MS peptide data per time unit the HCTultra assures maximum information from your samples, leading to a remarkable increase in peptide/protein identifications and database scoring. Intelligence Simultaneously the quality of MS/MS data reaches new heights due to new designs of smart precursor selection tools. The new PhosphoScan™ can easily detect phosphopeptides in a single LC-MS/MS run. Besides the well-established Smart ICC technology, PeptideScan™ allows on-the-fly selection of 2+/3+ charged peptide ions. For small molecule applications, SmartFrag™ and fast +/- switching provides highly reproducible MSn spectra for Librarysearch. Precision With the best mass accuracy available among ion traps, the HCTultra is an excellent instrument for de novo sequencing applications. Equipped for transforming speed into information Millions of MS/MS spectra, acquired with ease by HCTultra, are handled conveniently by ProteinScape™ the most sophisticated bioinformatics tools available. Furthermore, true non-redundant protein lists and reports are generated and fully automated screening for a large set of modifications may be initiated. Even automated phosphopeptide detection is possible with the new HCTultra. Bruker Daltonics again redefines the leadership in LC based MSn instruments with the new HCTultra. Unrivalled speed, sensitivity and mass accuracy are complemented with smart, sophisticated software tools to get the most out of every important sample. The HCTultra features Compass™, Bruker Daltonics’ comprehensive software environment for integrated LC/MS control, data acquisition, processing and interpretation. The optional Compass Security Pack™ allows ion trap productivity in regulated environments. >>>
View the product on bdal.com Bruker Daltonics Inc Groupe - Bruker Optics
MALDI-TOF & TOF/TOF MS - MICROFLEX

MALDI-TOF & TOF/TOF MS - MICROFLEX

Microflex The highest performance benchtop MALDI-TOF MS The microflex™ is designed as an affordable, yet powerful benchtop system that is convenient for many life-science laboratories. No-compromise performance on the bench The microflex takes advantage of Bruker Daltonics’ long standing expertise in providing the highest performance mass spectrometers. The unique design of the microScout ion source and the gridless reflectron give the microflex superior resolution, as well as excellent mass accuracy and outstanding sensitivity. Advanced design The modular design offers several instrument configurations to fulfill different requirements for peptide/protein identification and characterization, biomarker discovery or oligonucleotide analysis. Should your requirements grow or change over the years, the system can be upgraded to meet new analytical challenges. Intuitive instrument control The microflex features our integrated Compass software environment for easy operation in multi-instrument laboratories. All functions from automated acquisition to in-depth analysis via highly sophisticated bioinformatics software are provided. Unique AnchorChip technology The powerful proprietary AnchorChip technology provides homogeneous, exactly-positioned samples on the MALDI target for robust and rapid automated data collection, as well as a sensitivity boost by up to two orders of magnitude. Compatibility and automation Compatibility with laboratory robots (e.g. map II) is assured by the new microScout MALDI target plates, featuring 96 position geometry to sample from industry standard microtiter plates. >>>
View the product on bdal.com Bruker Daltonics Inc Groupe - Bruker Optics
MALDI-TOF & TOF/TOF MS - MICROFLEX LT

MALDI-TOF & TOF/TOF MS - MICROFLEX LT

Microflex LT The routine benchtop MALDI-TOF MS Routine analysis in Expression Proteomics Clinical Proteomics Functional Genomics The microflex™ LT is an affordable, bench-top MALDI-TOF mass spectrometer for clinical proteomics, as well as for the routine analysis of peptides, proteins and other large molecules. Due to its gridless ion source, this new instrument provides excellent sensitivity in both positive and negative ion mode. The linear-mode microflex LT is a robust and easy-to-use system for many clinical and life-science laboratories. It operates under the integrated Compass™ software for intuitive operation by non-expert users and in multi-instrument laboratories, with a comprehensive bioinformatics software suite. The microflex LT benefits from Bruker Daltonics’ patented AnchorChip™ technology which provides exactly-positioned samples on the MALDI-target for robust automatic measurements, as well as a sensitivity boost by up to two orders of magnitude. The microflex LT system can be an integral module of the CLINPROT™ solution for biomarker discovery and clinical proteomics. CLINPROT is an integrated set of tools for peptide and protein biomarker discovery, identification and validation, including automated magnetic bead based sample preparation methods, and ClinProTools™ comprehensive analysis, visualization and model building software for clinical research. For pharmaceutical customers, the microflex LT system offers software tools to support customers in achieving 21 CFR Part 11 compliance. Bruker Daltonics also offers optional IQ, OQ and PV services to FDA-regulated customers. Technical Data MALDI source microScout Ion Source with state-of-the-art pulsed ion extraction (PIE™) Target area exactly ¼ of industry standard microtiter plates Various 96-spot target types available for specific applications Compatible with Bruker Daltonics sample preparation robotics Nitrogen laser with variable repetition rate up to 20 Hz Patented AnchorChip MALDI target technology for fast automation, increased sequence coverage and 10–100 fold sensitivity increase over stainless steel target holder TOF Analyzer linear only configuration positive/negative acceleration voltage No maintenance oil-free vacuum technology WhisperMode™ erases noise pollution in the lab 500 MHz Digitzer board >>>
View the product on bdal.com Bruker Daltonics Inc Groupe - Bruker Optics


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